KnotBody® Technology: Engineering Ion Channel–Modulating Antibodies via Knottin Integration into Antibody Loops
9:00 am - Thursday 24th September 2026
- Overview of the KnotBody Platform: A novel approach enabling potent, selective, and durable modulation of ion channels
- Lead Optimisation Highlights: Progress towards optimised KnotBody candidates targeting autoimmune diseases, demonstrating enhanced efficacy and developability
- Platform Versatility: Evidence of broad applicability across diverse target classes, underscoring the flexibility of the KnotBody platform