Lipid-dependence of Kv7 Activator Drugs: Insights for Selective & Effective Potassium Channel Therapeutics

• Defining how Kv7 activators modulate voltage-gated potassium channels to improve mechanistic understanding of ion channel pharmacology
• Revealing how membrane lipid composition influences drug activity, specificity, and channel regulation across Kv7 subtypes
• Applying molecular-level insights to understand selectivity, potency, and efficacy of potassium channel targeted therapeutics for epilepsy and pain disorders

Speakers:

Harley Kurata

Professor

University of Alberta