Selective Sodium Channel Modulation to Deliver Meaningful Clinical Benefits in Chronic Chemotherapy-Induced Neuropathic Pain

  • A late-stage Phase 2 development program applying tetrodotoxin-based sodium channel modulation to treat chemotherapy-induced neuropathic pain
  • Achieving durable pain reduction while minimizing CNS and systemic safety liabilities associated with chronic pain therapies
  • Establishing clinical proof of concept for selective ion channel modulation in nonopioid pain management